3arm and 4arm Heterofunctional PEGs
JenKem Technology’s 3arm and 4arm heterofunctional PEG Derivatives are designed as linkers for Antibody-Drug Conjugates (ADCs), as they facilitate the coupling of high ratios of drug molecule per antibody. ADCs conjugated via multiarm PEGs deliver a higher concentration of drug to targets for each antibody-antigen interaction, and exhibit improved solubility and PK/PD profile.
JenKem Technology’s 3arm and 4arm heterofunctional PEG products with molecular weights and functional groups not listed in our online catalog may be available by custom synthesis. Please inquire at tech@jenkemusa.com about pricing and availability.
JenKem Technology provides GMP grade PEG derivatives and bulk orders via custom synthesis, offering the opportunity to match customers’ special quality requirements. JenKem Technology is capable of development and synthesis of a wide range of GMP PEG derivatives starting at 200g up to 40 kg or greater batches, under ISO 9001 and ISO 13485 certified quality management system, following ICH Q7A guidelines. For inquiries on cGMP production of PEG derivatives please contact us at tech@jenkemusa.com.